![]() ![]() It is still unclear whether PEG is the cause of the reported allergic reactions or whether the concentration of PEG in the vaccine is enough to cause a reaction. PEG, which is commonly found in laxatives, works in the vaccine as a protective coating for the mRNA molecule as it enters cells. Like the Pfizer vaccine, the Moderna COVID-19 vaccine contains an ingredient called polyethylene glycol (PEG), which has raised concerns regarding its potential to induce an allergic reaction. The vaccine fact sheet lists the following potential symptoms of a severe allergic reaction: Out of 7,581,429 Moderna vaccine doses administered, there have been 19 reports of anaphylaxis, fewer than 3 cases per million. Most of those who receive immediate care respond well to treatment, and their condition quickly improves, the agency adds.Īllergic reactions, severe and otherwise, have been reported as possible side effects of the vaccine, as a response to certain ingredients in the vaccine.Īnaphylaxis, a severe allergic reaction, is a rare side effect of vaccination. The symptoms include chest pain, shortness of breath, and “feelings of having a fast-beating, fluttering, or pounding heart.”Īccording to the CDC, these side effects within the heart are most likely to occur in adolescents and young adults. The federal agency also advises that those who do experience myocarditis or pericarditis symptoms after vaccination should seek medical attention immediately. In the patient fact sheet for the Moderna vaccine, the FDA notes that symptoms of myocarditis or pericarditis tend to appear “within a few days following receipt of the second dose.” However, the FDA, adds, these side effects are very unlikely to occur in most people. Rare side effects: Myocarditis, pericarditisįollowing some reports of myocarditis, or inflammation of the heart muscle, and pericarditis, which is inflammation of the lining outside the heart, after the receipt of mRNA vaccines, the FDA added revisions to both the patient and healthcare provider fact sheets for the Moderna vaccine. The authors of the report note that COVID arm is uncommon, not harmful, and recedes spontaneously or with the use of steroids or antihistamines. This case report describes the experiences of four people who developed COVID arm 7–10 days after receiving the first dose of the Moderna vaccine. Known as “ COVID arm,” the rash can appear several days after the vaccination. ![]() There have also been reports of people experiencing a red, itchy, swollen, or painful rash at the injection site. This study notes that after the second dose, 82% of Moderna vaccine recipients reported injection site reactions, compared with 69% of Pfizer vaccine recipients. People who have had other authorized COVID-19 vaccines have also reported these side effects.Īmong recipients of mRNA vaccines, however, there have been more frequent reports of side effects from people who have had the Moderna vaccine. swelling of armpit lymph nodes, specifically (19.8%).Recipients also reported the following injection site reactions: The clinical trials found that side effects were more commonly reported after the second dose and lasted around 2–3 days. Also, we have included the percentages of frequency reported in Moderna’s phase 3 clinical trial data: doi:10.1001/ FDA’s fact sheet for this vaccine lists the following general side effects. Delayed localized hypersensitivity reactions to the Moderna COVID-19 vaccine: a case series. Johnston MS, Galan A, Watsky KL, Little AJ. Reactogenicity following receipt of MRNA-based COVID-19 vaccines. The second dose of a COVID-19 vaccine: Side effects, why they happen, and how to treat them.Ĭhapin-Bardales J, Gee J, Myers T. 5 exercises to reduce arm soreness after the COVID-19 vaccination. Sheltering Arms Physical Rehabilitation Center. Use of COVID-19 vaccines after reports of adverse events among adult recipients of Janssen (Johnson & Johnson) and mRNA COVID-19 vaccines (Pfizer-BioNTech and Moderna): Update from the Advisory Committee on Immunization Practices - United States, July 2021. Rosenblum HG, Hadler SC, Moulia D, et al. Local reactions, systemic reactions, adverse events, and serious adverse events: Pfizer-BioNTech COVID-19 vaccine. Interim considerations: preparing for the potential management of anaphylaxis after COVID-19 vaccination.Ĭenters for Disease Control and Prevention. Possible side effects after getting a COVID-19 vaccine.Ĭenters for Disease Control and Prevention. doi:10.1001/jamadermatol.2021.1214Ĭenters for Disease Control and Prevention. Delayed localized hypersensitivity reactions to the Moderna COVID-19 vaccine: A case series. ![]()
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